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Good Sam stars Sophia Bush as Dr. Sam Griffith, a gifted young heart surgeon looking to come into her own personally and professionally. Sam is overshadowed and undermined by her renowned and arrogant boss Dr. Rob "Griff" Griffith (Jason Isaacs), who also happens to be her father. The tension is building. Good Sam premieres Wednesday January 5 on CBS.。在一个密闭的空间内，五个身份各异的人陆续从昏迷中醒来，但却发现自己失去了记忆，完全不记得自己是谁。他们发现别墅的门窗都被反锁，五人决定齐心合力逃出密室，在合作途中，随着时间的流逝，五个人逐渐恢复了一些模糊的记忆，发现彼此之间有一些联系，五个人开始猜疑对方的身份，而最终寻找到的一个致命的线索，导致了他们互相残杀，于是一场你死我活的寻找记忆真相的游戏，在密闭空间中展开.。